Lactose Intolerance Research Today is a free monthly online journal that collates and summarizes the latest research about Lactose Intolerance, including details on symtpoms, infants, causes, treatment, diet.
Surface proteins of bacteria of the genus Bifidobacterium .
Dylus E, Buda B, Górska-Frączek S, Brzozowska E, Gamian A
Instytut Immunologii i Terapii Doświadczalnej im. L. Hirszfelda, Polskiej Akademii Nauk we Wrocławiu.
Beneficial effects due to the presence of probiotic bacteria of the genus Bifidobacterium in the human intestinal tract are still an interesting object of study. So far activities have been confirmed of bifidobacteria in stimulation of the host immune system, stimulation of tumor cell apoptosis, improvement of bowel motility, alleviation of symptoms of lactose intolerance, cholesterol lowering capacity, prevention and treatment of diarrhea and irritable bowel syndrome, alleviation of allergy or atopic dermatitis, maintenance of homeostasis of the intestine, and stimulation of the development of normal intestinal microflora in infants. A multitude of therapeutic properties encourages researchers to investigate the possibility of using the potential of Bifidobacterium in the prevention and treatment of other conditions such as rheumatoid arthritis and depression. Although it is known that the beneficial effects are due to intestinal mucosal colonization by these bacteria, the cell components responsible for the colonization are still not determined. In addition to the beneficial effects of probiotic administration, there were also negative effects including sepsis. Therefore research has been directed to identify specific components of Bifidobacterium responsible for probiotic effects. Currently researchers are focused on identifying, isolating and evaluating the properties of surface proteins that are probably involved in the adhesion of bacterial cells to the intestinal epithelium, improving colonization. This paper is an overview of current knowledge on Bifidobacterium surface proteins. The ways of transport and anchoring proteins in Gram-positive bacterial cells, the assembly of cell wall, and a description of the genus Bifidobacterium are presented.
Published 12 June 2013 in Postepy Hig Med Dosw (Online), 67: 402-12.
Articles on Lactose Intolerance published 10 June 2013:
Approximately 2.5% of young children are allergic to cow's milk. In this study, milk protein hydrolysates made from full-cream milk via enzymatic hydrolysis played a positive role in regulating the immune system of ICR mice. Milk protein hydrolysates enhanced immunity in mice by stimulating host immunity, probably by increasing the weight of certain immune system organs, improving the level of hemolysin in serum, and enhancing the phagocytosis of macrophages. Milk protein hydrolysates have the ... [Abstract] [Full-text]
Articles on Lactose Intolerance published 6 June 2013:
Heated allergens and induction of tolerance in food allergic children. Nutrients, 5(6): 2028-46.
Food allergies are one of the first manifestations of allergic disease and have been shown to significantly impact on general health perception, parental emotional distress and family activities. It is estimated that in the Western world, almost one in ten children have an IgE-mediated allergy. Cow's milk and egg allergy are common childhood allergies. Until recently, children with food allergy were advised to avoid all dietary exposure to the allergen to which they were sensitive, in the ... [Abstract] [Full-text]
Abstract Purpose: The rate of cow's milk allergy diminishes with age. There is not enough information concerning geographical trends in persistent cow's milk allergy in children. The objective of the study was to evaluate the prevalence of persistent cow's milk allergy in children previously diagnosed with IgE-mediated cow's milk allergy (CMA). Material/Methods: Diagnosis of cow's milk allergy was established by a medical history of symptoms associated with exposure to cow's milk, positive skin ... [Abstract] [Full-text]
Articles on Lactose Intolerance published 5 June 2013:
Factors associated with the timing of introduction of complementary feeding: the Generation R Study. Eur J Clin Nutr, 67(6): 625-30.
Background/objectives:Many parents do not follow recommendations for the timing of introduction of complementary feeding. The aim of this study was to identify determinants associated with the timing of introduction of complementary feeding in a multiethnic birth cohort.Subjects/methods:Subjects were 3561 mothers and infants participating in a prospective cohort study. The timing of introduction of complementary feeding and maternal and infant characteristics were obtained by parent-derived ... [Abstract] [Full-text]
Articles on Lactose Intolerance published 4 June 2013:
Early life events predispose the onset of childhood functional gastrointestinal disorders. Rev Gastroenterol Mex, 78(2): 82-91.
A comparison between two different in vitro basophil activation tests for gluten- and cow's milk protein sensitivity in irritable bowel syndrome (IBS)-like patients. Clin Chem Lab Med, 51(6): 1257-63.
Abstract Background: The diagnosis of food hypersensitivity (FH) in adult patients with gastrointestinal symptoms, beyond the immediate IgE-mediated clinical manifestations, is very often difficult. The aims of our study were to: 1) evaluate the frequency of FH in patients with irritable bowel syndrome (IBS)-like clinical presentation; and 2) compare the diagnostic accuracy of two different methods of in vitro basophil activation tests. Methods: Three hundred and five patients (235 females, age ... [Abstract] [Full-text]
Articles on Lactose Intolerance published 3 June 2013:
Allergies in high-risk schoolchildren after early intervention with cow's milk protein hydrolysates: 10-year results from the German Infant Nutritional Intervention (GINI) study. J Allergy Clin Immunol, 131(6): 1565-1573.e5.
Articles on Lactose Intolerance published 31 May 2013:
GOALS AND BACKGROUND:: Hypolactasia affects over half of the world population. Diagnosis remains problematic as currently available tests, such as the hydrogen breath test, have low reliability and lactose intolerance symptoms are unspecific. We evaluated the diagnostic performance and safety of a new noninvasive diagnostic test based on urine or serum measurement of D-xylose after lactase cleavage of orally administered 4-galactosylxylose (gaxilose). STUDY:: In a multicentre, open-label, ... [Abstract] [Full-text]
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